Recent research from the top orthopaedic journals — auto-curated from PubMed and refreshed throughout the day.
Lee TC, Kao CM, Lin YW, et al
Post-traumatic knee osteoarthritis develops following acute joint injuries and can progress rapidly, causing significant morbidity. Intra-articular hyaluronic acid injections are a common treatment,…
Matsuo R, Toda Y, Inoue F, et al
Kocak S
Sardar ZM, Miller R, Reyes JL, et al
Retrospective analysis. To describe normative cervical sagittal alignment and to propose a classification system to guide clinical assessment and surgical planning. Optimizing alignment is a key goal…
Huang D, Wang Z, Jian-Wen Chen M, et al
Retrospective study. To evaluate whether the extent of correction influences outcomes following adult spinal deformity (ASD) surgery using a matched-pair analysis. Alignment targets are often based…
Al-Saidi N, Al-Saidi N, Nguyen R, et al
Systematic review and meta-analysis. To assess how operative order affects clinical outcomes and complications in patients with concomitant lumbar spinal and hip pathologies. Concomitant lumbar…
Hall M, Ferreira P, Eyles J, et al
Sleep disturbance is highly prevalent in people with osteoarthritis (OA) yet it is rarely considered in routine care. Emerging evidence suggests that sleep disturbance contributes to heightened…
Coryell PR, Fernandez Davila JG, Yanke AB, et al
The purpose of this study was to screen FDA-approved compounds for potential disease-modifying osteoarthritis drugs. An FDA-approved library of 2679 compounds was used for a high throughput screen…
Fairley JL, Kapoor M, Sharma D
Generative artificial intelligence (GenAI) is a transformative tool capable of producing realistic synthetic data, modeling complex data, and translating large volumes of information into clinically…
Huesa C, McGrath S, Dunning L, et al
Protease-activated receptor 2 (PAR2) plays a pivotal role in the early stages of surgery-induced murine osteoarthritis (OA). However, it remains unclear whether modulation of PAR2 offers sustained,…
Guo M, Wang S, Li X, et al
Retrospective cohort study. To determine whether multilevel L1 to S1 paraspinal muscle fatty infiltration (FI) and a posterior paraspinal radiomics signature improve prediction of prolonged length of…
Ai Y, Zhu C, Wang J, et al
Prospective observational cohort study. To prospectively evaluate the utility of traditional and single-level vertebral bone quality (VBQ) scores for preoperative bone mineral density (BMD)…
Backes J, Pabinger C, Lothaller H, et al
In 2015, we reported rapid growth and variation in knee arthroplasty across OECD countries, especially in patients ≤64 years, projecting a four-fold increase by 2030. Since then, clinical…
Drummen SJJ, Aitken D, Otahal P, et al
To determine the association between Criteria for the Early Diagnosis of Knee osteoarthritis (CREDO) defined early-stage knee osteoarthritis (KOA) and the prevalence of MRI structural abnormalities,…
Murillo-Saich JD, Mannochio-Russo H, Sala-Climent M, et al
To evaluate the relationship between bile acids (BAs) and synovitis in knee osteoarthritis (KOA). Radiographic KOA patients with complete datasets were included. WOMAC total and subscores were…
Satriano L, Frederiksen P, Karsdal MA, et al
To evaluate the association of neoepitopes from type I and II collagen with knee osteoarthritis (OA) progression phenotypes using data from the OA-FNIH biomarker consortium, with comparison to…
Jones GMC, Mosey H, Hopkinson M, et al
To characterize the deviation from normal bone architectural patterns in OA using an innovative, 3D whole bone mapping approach that utilises micro-computed tomography (µCT) scans of femoral…
Katz JN, Yang HY, Edwards R, et al
Symptomatic meniscal tear and knee osteoarthritis (OA) are commonly accompanied by pain, which may arise from nociceptive mechanisms and from processes, referred to as sensitization, that alter and…
Mai YX, Chen JL, Chen F, et al
The long intergenic non-coding RNA Linc01152 is a recently identified lncRNA whose functional involvement in osteoarthritis (OA) remains largely understood. In the present study, we tried to…
Woods S, Bates N, Cain S, et al
Multiple epiphyseal dysplasia (MED), caused by mutations in MATN3, is a chondrodysplasia affecting the cartilage growth plate and is characterised by delayed epiphyseal ossification, short stature,…
Lowe T, Lee W, Miller EY, et al
Alterations in cartilage mechanical properties may signal early degenerative changes preceding clinical or radiographic evidence of osteoarthritis. MRI-based techniques may detect these early…
Hartog M, Korsten SGPJ, Popa CD, et al
This study primarily assessed effects of Sustained Release Calcium Butyrate (SRCaBu) on gut microbiome composition and function in hand OA patients. Secondary objectives included its impact on hand…
Moews LD, Kunze KN, Thamrongskulsiri N, et al
Glucagon-like peptide-1 agonists (GLP-1s) are increasingly prescribed for type 2 diabetes mellitus (T2DM) and obesity, with over 12% of the United States population reported to being using this…
Qualter JM, Chertok AN, Buhler A, et al
Biomechanical loading is a known contributor to osteoarthritis (OA) pathogenesis, and one of the few modifiable risk factors. Thus, research on biomechanics offers an opportunity to gain valuable…
Uno T, Mura N, Oishi R, et al
Arthroscopic Bankart repair (ABR) using the knotless double-row technique, called the knotless double anchor footprint fixation (DAFF), involves inserting anchors into the scapular neck, passing…
Rhee SM, Min YK, Park JH, et al
Vitamin D is crucial in musculoskeletal health, supporting bone, tendon, and muscle function. However, its localized delivery for tendon healing and muscle regeneration remains underexplored. We…
Secci G, Mouchantaf M, Biegun M, et al
Bony increased-offset-reverse shoulder arthroplasty (BIO-RSA) has shown promising short- to medium-term results; however, long-term outcomes are lacking. The goal of the present study was to report…
Walsh WR, Batista J, Lovric V, et al
Clinical studies support that augmenting rotator cuff repair through the induction of new host tissue can prevent gapping or retear by increasing tendon thickness and strength. To date, most implants…
Wolf BR, Dunn WR, VanTienderen RJ, et al
The purpose of this study was to analyze rates of recurrent shoulder instability and subsequent surgery, as well as the risk factors associated with those outcomes, in a large prospective multicenter…
Kolakowski L, Stadecker M, Kucharik M, et al
Introduction of reverse total shoulder arthroplasty (rTSA) has contributed to a large increase in primary rTSA volume. The impact of rTSA on revision TSA has not been well described. This study aims…
Shang G, Mu Y, Zhao Z, et al
Although risk factors for recurrent instability following arthroscopic Bankart repair (ABR) have been extensively investigated in the general population, research focusing specifically on military…
Lau J, Ting RS, Lam PH, et al
Retear following rotator cuff repair is relatively common. Onlay biological grafts offer a potential solution, as a source of additional healing. The purpose of this study was to determine whether…
Agaisse T, Toavs T, Covarrubias O, et al
Despite extensive study of the treatment of glenohumeral osteoarthritis (GHOA), there has been little investigation of the progression of the pathoanatomy, and associations between longitudinal…
Chang K, Toavs T, Covarrubias O, et al
Reverse total shoulder arthroplasty (rTSA) is an alternative to anatomic total shoulder arthroplasty for the treatment of primary glenohumeral osteoarthritis (GHOA) with intact rotator cuff. The…
Aibinder WR, Mazeh M, Elwell JA, et al
There has been a trend toward the use of shorter humeral components with the goal of preserving bone, decreasing operative time, and a theoretical decrease in stress shielding. The purpose of this…
Pandy MG, Yang K, Guan S, et al
Reverse total shoulder arthroplasty (rTSA) designs have evolved from Grammont's original design due to the sequelae of postoperative problems that arose. However, the impact of rTSA design on…
You DZ, Rudisill SS, Baird M, et al
Strut allograft reconstruction represents an appealing option to address bone deficiency in revision total elbow arthroplasty (TEA), offering immediate structural support and potential for graft…
Kriechling P, Bösch M, Hochreiter B, et al
The available data on heterotopic ossification (HO) following implantation of reverse total shoulder arthroplasty (rTSA) is limited. It was the aim of this study to determine occurrence of HO…
Liaghat B, Borg SAM, Haugegaard T, et al
More older adults with displaced proximal humerus fracture (PHF) are managed nonsurgically and referred to supervised rehabilitation, but its effectiveness is unknown. The primary objective of this…
Tytherleigh-Strong G, Van Rensburg L
The majority of patients with symptomatic sternoclavicular joint (SCJ) osteoarthritis (OA) can be successfully treated nonoperatively. For patients who remain symptomatic, an arthroscopic or open SCJ…
Kim H, Lee H, Lim TK, et al
Accurate positioning of the glenoid baseplate and peripheral screws is critical in reverse total shoulder arthroplasty (rTSA). Patient-specific instrumentation (PSI) has been introduced to improve…
Constantin H, Rialet Q, Suárez Jiménez LJM, et al
Patients with massive irreparable rotator cuff tears sometimes experience significant functional impairment due to external rotation deficits, categorized as isolated loss of external rotation (ILER)…
Khatri K, Gupta N, Bansal N, et al
Lateral epicondylitis (LE) is commonly treated with triamcinolone injections, but ketorolac, a nonsteroidal anti-inflammatory drug (NSAID), may offer a safer alternative. This non-inferiority trial…
Chen P, Prosser M, Phillips B, et al
The COVID-19 pandemic accelerated the demand for remote assessment tools in rehabilitation, especially the need for accurate and reliable technologies to measure shoulder range of motion (ROM)…
Matsui T, Seo K, Miyazaki T, et al
Medial elbow injuries, particularly ulnar collateral ligament injuries, are a major concern in youth and adolescent pitchers. Elbow varus torque (EVT) is commonly used as an index of medial valgus…
Lopiz Y, Bartrina A, Landero A, et al
Reverse total shoulder arthroplasty (rTSA) has become the standard surgical option for managing complex proximal humerus fractures (PHFs) in elderly patients. Despite its widespread use,…
Cheow X, Schramm S, Voss A, et al
Repair and augmentation techniques have been successfully applied in the treatment of acute ligament injuries causing elbow instability. This study evaluates whether the chronicity of elbow…
Denard AD, Werner BC, Schuette HB, et al
The purpose of this investigation was to evaluate the impact of scapular neck length (SNL) on outcomes following reverse total shoulder arthroplasty (rTSA) using a lateralized 135° implant…
Nahr A, Hanish S, Colatruglio M, et al
The annual incidence of reverse total shoulder arthroplasty (rTSA) indications has surpassed that of anatomic total shoulder arthroplasty. Its unique complications include prosthetic dislocation,…
Scanaliato JP, Williams T, Garelick S, et al
Reverse total shoulder arthroplasty (rTSA) is a well-established treatment for cuff tear arthropathy and consistently restores active forward elevation. However, when there is a deficiency of the…
Diez Sánchez B, Palacios-Díaz L, Antuña SA, et al
Radial head replacement (RHR) is a well-established treatment for comminuted fractures (radial head fracture). In most cases, it provides satisfactory long-term functional results. However, some…
Okubo T, Nagoshi N, Yamane J, et al
Multicenter prospective cohort study. To evaluate the influence of preoperative mental health status on clinical outcomes following surgery for degenerative cervical myelopathy (DCM). Surgical…
Zhou X, Luo P, Jiang H
Joshi T, Katakam A, Azer A, et al
Physician reimbursement for orthopedic procedures, such as total shoulder arthroplasty (TSA) and related revision surgeries, has been subject to economic pressures over the past 2 decades.…
Ito Y, Mihara H, Tatara Y, et al
Multicenter retrospective observational study. To quantitatively evaluate spinal cord pulsatile motion during anterior cervical decompression and fusion (ACDF) and identify factors affecting spinal…
Mutyaba I, Kleinsmith R, Banfield N, et al
Retrospective case series. The primary objective of this study is to assess the change in patient-reported outcomes from baseline to 3 months following lumbar discectomy for lumbar disc herniation.…
Djurasovic M, Glassman SD, Mathew J, et al
Retrospective observational cohort. To determine the incidence of and risk factors for postoperative cognitive dysfunction (POCD) following multilevel spine fusion. POCD is a serious, common and…
Capek V, Brisby H, Westin O
Agreement analysis of retrospectively collected data. To perform an agreement analysis between the Sanders maturity scale and pelvic maturity indicators in patients with idiopathic scoliosis. A…
Asada T, Boddapati V, Omurzakov A, et al
Retrospective analysis. To compare clinical outcomes of minimally invasive transforaminal lumbar interbody fusion (MIS-TLIF) among patients with different radiographic difficult spondylolisthesis.…
Abbasian M, Moteshakereh SM, Zarei H, et al
To investigate the clinical and radiographic outcomes of revision anterior cruciate ligament reconstruction (rACLR) combined with anterior closing-wedge high tibial osteotomy (ACWHTO) for posterior…
Elhassan B
Asturias AM
Wang D, Davies J
Sierra RJ
Beksaç B
Ricciardi BF
Bakhshi M, Lux A, Mueller MM, et al
To investigate whether clinically failed anterior cruciate ligament (ACL) reconstructions can be accurately identified using magnetic resonance imaging (MRI). This prospective case series included 81…
Hurtado-Avilés J, Lajara-Marco F, Moya-Angeler J, et al
Minor variations in radiographic measurements of variables underlying the coronal plane alignment of the knee (CPAK) classification can alter its categorisation. Accordingly, this study introduces a…
Hsu CJ, Morgan JJ, Callahan DM, et al
Evidence describing movement strategies during bilateral functional tasks after medial patellofemoral ligament (MPFL) reconstruction is limited, highlighting the need for biomechanical assessments to…
Biswas A, Gaurav A, Chattopadhyay A, et al
This study evaluated the maturation of the peroneus longus (PL) tendon autograft by quantifying the key diffusion tensor imaging (DTI) parameters: fractional anisotropy (FA) and apparent diffusion…
Waldén J, Reito A, Niemeläinen M, et al
To assess whether coronal plane alignment of the knee (CPAK) is associated with functional outcome of total knee arthroplasty (TKA) and identify factors predicting functional outcomes during 10 years…
Medvecky MJ, Ayhan EM, Salandra JM, et al
Knee dislocations (KDs) can be limb-threatening injuries that may require a temporising knee-spanning external fixator (KSEF) for stabilisation. Precise indications for this commonly utilised…
León-Muñoz VJ, Moya-Angeler J, Santonja-Medina F, et al
The coronal plane alignment of the knee (CPAK) classification is based on fixed cut-off values derived from the mechanical lateral distal femoral angle (LDFA) and the medial proximal tibial angle…
Romero-Padron MA, Kallman T, Amirtharaj M, et al
Persistent, static anterior tibial translation (sATT) alterations following anterior cruciate ligament reconstruction (ACLR) may influence cartilage health. T2 relaxation times and serum biomarkers…
Bouterse AM, Pruneski JA, Oettl FC, et al
The integration of artificial intelligence (AI)-equipped tools into electronic health record (EHR) platforms may drive the evolution of orthopaedic diagnosis and decision-making, leveraging big data…
Vivekanantha P, Son H, Bernardini L, et al
Large language models (LLMs) are a form of artificial intelligence (AI) that have emerged as potential tools to augment systematic review workflows. This study aimed to evaluate GPT-5 as a third…
Shelbaya S, Trasatti E, Macey R, et al
Evaluate the association between posterior tibial slope and survivorship following meniscal allograft transplantation and to determine whether a slope threshold is associated with increased risk of…
Mazy D, Cance N, Dan MJ, et al
This study aimed to evaluate anterior cruciate ligament (ACL) graft rupture in a selective approach to lateral extra-articular tenodesis (LET), with a focus on the impact of posterior tibial slope…
Sasanelli F, Zordan R, Suzuki L, et al
Patellofemoral instability (PFI) has been associated with multiple anatomical risk factors. The recent development of accurate quadriceps muscle measurements using three-dimensional imaging…
Szaro P, Meunier A, Bokwa-Dabrowska K, et al
Incomplete recovery with persistent muscle weakness is frequently observed following Achilles tendon rupture. The mechanisms for this weakness remain unclear, but tendon elongation has been suggested…